When we say DefenAge, we say revolution. DefenAge is a skincare product known for its clinically proven anti-aging effects. And, what makes DefenAge thrive with the anti-aging claims is their ingredient called defensins.
Defensins are peptides produced naturally in the skin and other parts of the body. Moreover, peptides are compounds composed of two or more amino acids linked to an amino compound.
At first, defensins were only discovered for their effects in healing diabetes. But recently, scientists have found out about defensins’ healing properties and immunity-boosting function to the skin.
DefenAge: The pioneer in anti-aging through defensin
DefenAge is the first company to use this revolutionary ingredient in reducing the effects of aging. The brand targets stubborn lines wrinkle depth and size, pore size, pigmentation, and spots through a liposomal system which assists the said peptides in skin repair. This combination of technique and substances help regenerate healthier skin cells, despite old age.
Among the fourth-generation skincare products, DefenAge is the only one that uses stem cell skincare, addressing up to fifteen signs of aging in just six weeks!
These concerns are:
- Clogged pores
- Contour definition
- Dark spots
- Fine lines
- Loss of firmness
- Loss of moisture
- Rough texture
- Skin clarity
- Skin softness
- Surface imperfections
- Uneven skin tone
The DefenAge History
DefenAge was founded in 2014 by American medicine experts. Their research on anti-aging became the foundation of the brand’s formulas ever since. The DefenAge team also aspires to be the #1 in the world in terms of anti-aging skincare.
But, DefenAge did not just discover their breakthrough formula overnight. It took many years to arrive at what we know of them now finally. Below, we have laid out DefenAge’s research, discovery, and development timeline to showcase the company’s dedication towards being the world’s number one:
2014: Two doctors who studied cell biology and regenerative medicine have discovered the anti-aging properties of defensins. These molecules naturally awaken sleeping skin cells and start a wound-healing response to create new skin.
This research prompted the idea of using defensins as a strategy in combating skin aging, and eventually, the company’s creation.
2015: With its innovative strategy leading its start, DefenAge released its first line of products to the professional market. The skincare products paved their way to plastic surgeons, dermatologists, and the aesthetics community and received warm and positive greetings.
2018: True to their scientific passion, the study conducted by the experts in DefenAge was published in the Journal of Drugs and Dermatology in 2018. The publishing of their design and study results was commended because they showcased professionalism, exceeding the industry’s expectations.
Moreover, their study paved the way for making professionals respect their products due to their scientific approach to skincare.
2019: In pursuit of their promise of meeting the highest standards, they have decided to launch their products to the public and started distributing them to local consumers. They made sure that they are continuously growing for their clients.
The DefenAge Values
DefenAge core values are in line with product safety, purity of their products, and transparency in their manufacturing process. They follow strict “Clean Beauty” standards, guidelines, and recommendations. Their products are also not tested on animals and do not contain any human or animal by-products; they are gluten-free.
Moreover, they help boost the US economy by providing jobs in their local community. And as an independent company that respects ethical considerations, they constantly improve their operations by ensuring that they follow sustainability practices and implement environmentally-friendly work strategies.
R&D: Research and DefenAge
As mentioned, DefenAge published their study designs in 2018. These publications made them carve a spot as a trusted brand by professionals. Thus, to give you a glimpse of what made the professionals swoon over DefenAge’s skincare technology, here is a quick summary of their study design and results:
The company recruited twenty-two men and women for the two studies: double-blinded placebo-controlled and open-label.
There were 10 participants in the double-blinded placebo-controlled study, with five persons per group. The participants had an average age of 56 years old, ranging from 48-68 years old. They also have Fitzpatrick’s skin types II, III, and IV.
On the other hand, the open-label study had 12 participants with an average age of 58 years old, ranging from 47-67 years old. Moreover, they have Firzpatrik’s skin types of I, II, III, and IV.
In this study, the participants were instructed to topically apply beta-defensin 3 supplemented with cosmetic base, synthetic liposome-incorporated alpha defensin five, and SPF 30 on their faces, necks, and behind the auricle of their ears, twice a day for six weeks.
To know the effects of DefenAge, the participants underwent skin testing and imaging evaluation at baseline on the 1st, 4th, and 6th weeks of the treatments. Individual skin health scores, such as wrinkles, evenness, pores, and oiliness before and after the treatment, were calculated using Quantificare ™ Clinical Imaging system. The researchers then compared data from this step with Quantificare’s Reference Population Database of normal skin aging, adjusted for sex, age, and skin type.
The participants were also subjected to evaluation for redness and dark spots and filled in a self-evaluation questionnaire.
The open-label group began the study with an almost “average” skin health score (above 58%) compared to the database.
In the fourth week, proponents saw a visible reduction of brown spots and wrinkles, and the team discovered a significant improvement in the skin evenness of the participants.
In the sixth week, the participants had an advanced skin score and reached 78%, which significantly improved compared with 58% at the beginning of the study. Based on an evenness parameter, which is a global measurement of the roughness of the skin surface that considers wrinkle size, pore size, and coarse texture of the skin, the participants showed a minus 18 years (plus or minus 4) in skin age. In more straightforward terms, for example, a participant who is 58 years old looked roughly 40 after the treatment.
Moreover, the subjective assessment of the participants also reflected these objective improvements. All of them (100%) noted significant improvement in their skin.
On the other hand, the participants of the double-blinded study were supplemented with formulations containing DefenAge’s performance ingredients. In the sixth week, they showed a significant decrease in wrinkles, visible lines, and a dramatic and visible improvement in their overall skin texture and skin tone. Lastly, the placebo group subjected to null-formulations did not showcase any signs of improvement.
With all the science behind DefenAge, there is no doubt that even skincare professionals patronize these products. Despite being distributed to consumers, sourcing DefenAge products could still be complicated. So if you are convinced with DefenAge’s anti-aging skincare magic and want to get a hand on their products, contact a trusted DefenAge dealer now!